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Wellbutrin for Depression.
The following information is intended to supplement, not
substitute, the expertise and judgment of your physician,
pharmacist or other healthcare professional. It should not be
construed to indicate that using Wellbutrin is safe or appropriate
for you.
People seeking depression relief should carefully evaluate
Wellbutrin information and side effects before deciding to take
Wellbutrin. Consult your healthcare professional before using
Wellbutrin.
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What is Wellbutrin used for? Bupropion hydrochloride is an
antidepressant of the aminoketone class that is chemically
unrelated to tricyclic, selective serotonin re-uptake inhibitor or
other antidepressants. Wellbutrin is used to treat depression
while Zyban is used as a smoking cessation aid. Wellbutrin is
sometimes prescribed for ADHD symptoms.
General Wellbutrin Precautions:
_ Wellbutrin can be habit forming and can produce
withdrawal symptoms.
_ Talk to your doctor about alcohol use before starting treatment
with bupropion hydrochloride. Alcohol may increase the risk of
having a seizure while taking bupropion. Avoid alcohol or drink it
only in moderation while taking Wellbutrin.
_ Never take more bupropion hydrochloride than is directed by your
doctor. Higher doses of bupropion hydrochloride may increase the
risk of a seizure.
_ Wellbutrin may cause dizziness. If you experience dizziness,
avoid driving, operating machinery, or performing other hazardous
activities.
_ Rise slowly when rising from a sitting or lying position to
prevent dizziness or possible falls.
_ Do not take Wellbutrin if you have taken a monoamine oxidase
inhibitor (MAOI) within the last 14 days. A dangerous drug
interaction can occur if bupropion hydrochloride is combined with
MAO inhibitors.
_ It is not known whether Wellbutrin will harm an unborn or
nursing baby. Do not take Wellbutrin if you are pregnant or could
become pregnant without first talking to your doctor.
_ Tell the doctor or dentist that you are taking Wellbutrin if you
are having surgery, including dental surgery.
_ Wellbutrin may impair judgment, thinking, or motor skills.
Patients using bupropion should exercise caution until they have
adapted to therapy.
_ If you skip the missed dose and take only the next one as
directed. Do not take a double dose of Wellbutrin. Overdose is
possible.
_ Too much bupropion hydrochloride can increase the risk of a
seizure. Do not be taking more than one product containing
bupropion hydrochloride at a time (Wellbutrin and Zyban SR).
FDA Warnings for Wellbutrin:
The FDA issued a public health alert for Wellbutrin in March 2004
warning that bupropion hydrochloride can lead to deeper depression
and suicide. The FDA
recommends that health care providers warn patients, their
families and their caregivers to be alert for agitation,
irritability, suicide and worsening depression while using
Wellbutrin. The FDA also recommends that health care providers
closely monitor adult and children treated with bupropion
hydrochloride for worsening of depression or suicidal tendencies,
especially at the beginning of therapy or when the dose either
increases or decreases.
Wellbutrin can cause serious
side effects. Only you can decide if Wellbutrin is the best
means of treating depression symptoms. It is important for people
currently taking Wellbutrin to discuss side effect concerns with
their physician.
Wellbutrin Side Effects:
_ Agitation.
_ Irritability.
_ Deepened depression.
_ Increased risk of suicide.
_ Seizures.
_ Change in sex drive or ability.
_ Impotence.
_ Loss of libido.
_ Difficulty urinating or frequent urination.
_ Rapid or irregular heartbeats.
_ Chest pain.
_ Shortness of breath.
_ Headache.
_ Drowsiness.
_ Weakness.
_ Anxiety.
_ Insomnia or sleeplessness.
_ Nightmares.
_ Dry mouth.
_ Tremors.
_ Restlessness.
_ Dizziness.
_ Itching.
_ Hives.
_ Ringing in the ears.
_ Weight gain or weight loss.
_ Excessive sweating.
_ Skin rash.
_ Flu-like symptoms such as aching muscles, fatigue, and
discomfort.
_ Fever.
_ Loss of coordination.
_ Muscle or joint pain.
_ Constipation.
_ Blurred vision.
Contact your doctor immediately if you experience: An
allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, face, or tongue; or hives). Stop taking
Wellbutrin and contact your doctor immediately or seek emergency
medical treatment if you also experience a fast or irregular
heartbeat or seizures. Contact your doctor immediately if you
experience yellowing of the skin or eyes.
Before taking Wellbutrin, tell your doctor if you have or have
had:
_ Seizures or epilepsy.
_ Head injury or brain or spinal column tumor.
_ Diabetes.
_ Liver disease.
_ Kidney disease.
_ Heart disease.
_ High blood pressure.
_ History of heart attack.
_ Suicidal thoughts.
_ Anorexia, bulimia or other eating disorders.
_ Drink alcohol.
_ Use street drugs or take a prescription benzodiazepine such as
Xanax, Valium or Restoril.
_ Glaucoma.
_ Enlarged prostate.
_ Difficulty urinating.
_ An overactive thyroid gland.
What should I avoid while taking Wellbutrin?
_ Alcohol may increase the risk of having a seizure while taking
Wellbutrin. Avoid alcohol or drink it only in moderation while
taking Wellbutrin.
_ Never take more Wellbutrin than is directed by your doctor.
Higher doses of bupropion hydrochloride may increase the risk of a
seizure.
Symptoms of overdose may include: Symptoms of a Wellbutrin
overdose include seizures, loss of consciousness, weakness,
hallucinations, rapid or irregular heartbeat, heart attack,
difficulty breathing or swallowing, dizziness, fainting, confusion
and blurred vision.
What other drugs will affect bupropion? Wellbutrin can
increase the effects of many other drugs, leading to serious side
effects. If taking Wellbutrin, talk to your doctor and pharmacist
before taking any prescription or over-the-counter medicines. Do
not take bupropion hydrochloride with the following medicines
without your doctor’s approval:
_ Other bupropion hydrochloride products.
_ Lithium.
_ MAO inhibitors.
_ Other antidepressants.
_ Carbamazepine
_ Cimetidine.
_ Insulin.
_ Levodopa.
_ Methylphenidate.
_ Ritonavir.
_ Theophylline.
Wellbutrin can also interfere with anticoagulants, antihistamines,
antipsychotics, diet pills, medication for high blood pressure,
seizures, asthma, colds, or allergies; oral anti-diabetic
medications, sedatives, sleeping pills, thyroid medications,
tranquilizers, and vitamins. Drugs other than the above listed may
also interact with Wellbutrin. Talk to your doctor and pharmacist
before taking any prescription, over-the-counter medicines or
natural supplements.
*This antidepressant drug
information does not endorse Wellbutrin, diagnose patients or
recommend therapy. The information contained herein is not
intended to cover all possible warnings, uses, precautions, drug
interactions, allergic reactions, or adverse side effects of
Wellbutrin. If you have questions about the drugs you are taking,
check with your health care provider or pharmacist. The
information provided should not be construed to indicate that
Wellbutrin is safe, effective or appropriate.
Do not stop taking Wellbutrin without first talking to your
doctor. Your doctor may need to gradually reduce the dose before
stopping Wellbutrin completely. Suddenly stopping bupropion
hydrochloride may cause unpleasant and potentially serious side
effects.
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