Zoloft Increases the Risk of Suicide.
SSRIs like Zoloft cause some people (3 to
5 percent) to experience a suicide related side effects. These
suicide side effects include suicidal thoughts, suicidal gestures
(typically cutting of the body), suicide attempts and actual death
by suicide.
People being treated with SSRIs like Zoloft have become violent
and suicidal. Others have complained of severe withdrawal
reactions.
The FDA in March 2004 issued a warning for Zoloft and other
antidepressants, stating that the drug can cause suicide and
violence in children and teenagers. This FDA public health
advisory places doctors, patients and families on notice to be
particularly vigilant for signs of worsening depression or suicide
thoughts at the beginning of anti-depressant therapy or whenever
the dose is changed.
The drugs listed in the FDA warning are all newer antidepressants:
Prozac, Paxil, Zoloft, Effexor, Celexa, Remeron, Lexapro, Luvox,
Serzone and Wellbutrin.
The FDA action follows Britain's version of the FDA citing in
December 2003 evidence of a twofold to threefold increase risk of
suicide and suicidal thinking in children and adolescents with the
SSRI drugs like Zoloft .
These two agency actions follow 16 years of long-standing
controversy about the possibility that SSRI antidepressants like
Zoloft might induce suicide tendencies in some patients. Reports
of unusual and severe reactions with SSRIs began shortly after
Prozac, the first SSRI, was introduced in 1988.
In 1990 two Harvard researchers and psychiatrists published an
article entitled: “Emergence of Intense Suicidal Preoccupation
During Fluoxetine Treatment.” This article, which appeared in the
American Journal of Psychiatry reported that persistent,
obsessive, and violent suicidal thoughts emerged in a minority of
patients treated with fluoxetine (Prozac).
Yale psychiatrist Dr. Robert A. King researched SSRI-induced
suicide risk in1991. His peer-reviewed article, “Emergence of
Self-Destructive Phenomena in Children and Adolescents during
Fluoxetine Treatment,” stated that “self-injurious ideation or
behavior appeared de novo or intensified during fluoxetine
(Prozac) treatment.”
SSRI manufacturers and the medical community have been aware that
SSRIs can cause people to kill themselves for a long time. Despite
the numerous studies linking increased suicide risk with SSRIs
like Zoloft , drug manufacturers continued to refute these claims.
As the suicide debate bubbles, so does the debate among doctors
and researchers about the effectiveness of SSRIs like Zoloft .
Most studies find that SSRIs are no more effective in fighting
teenage depression than sugar pills. Even in adults, SSRIs have
been found to offer only modest benefits. In about half of all
adult tests, the drugs prove no more effective than placebos.
These modest benefits are found in published studies. Researchers
have not been able to analyze a large amount of the data because
unfavorable studies are not made public.
GlaxoSmithKline, for instance, acknowledged that just one of its
nine studies of Paxil in children and adolescents has been
published. The one published study made only passing mention of
suicide and concluded that the drug was effective against
depression. According to the FDA, the combined results of all nine
trials show that the drug is not effective against depression in
patients under 18.
Unpublished studies of Effexor, for example, suggested the drug
increased suicide-related events such as suicidal thoughts or
attempts by 14 times compared with placebo.
Other drug companies similarly have withheld negative studies of
SSRIs, claiming that the studies are “trade secrets.” With
negative results not disclosed, physicians often believe the drugs
are more effective and safer than they actually are.
SSRIs like Zoloft have been found to increase the risk of suicide.
SSRIs like Zoloft are found to be no more effective than a sugar
pill. In addition to that, all pharmaceutical drugs cause side
effects ranging from mild to life-threatening.
In addition to the increased suicide risk, Zoloft can cause
serious side effects.
Addiction and subsequent
withdrawal symptoms also rank on the list of serious Zoloft
side effects. Zoloft has been linked to Parkinson’s Disease and
drug-induced stuttering. Weight
gain and sexual
dysfunction are common Zoloft side effects.
The natural antidepressant Deprex safely and effectively relieves
depression symptoms without side effects commonly associated with
pharmaceutical medications.
Do not stop taking Zoloft without first talking
to your doctor. Your doctor may need to gradually reduce the dose
before stopping Zoloft completely. Suddenly stopping Zoloft may
cause unpleasant and potentially serious side effects and
withdrawal symptoms.
*This antidepressant drug information does not
endorse Zoloft, diagnose patients or recommend therapy. The
information contained herein is not intended to cover all possible
warnings, uses, precautions, drug interactions, allergic
reactions, or adverse side effects of Zoloft. If you have
questions about the drugs you are taking, check with your health
care provider or pharmacist. The information provided should not
be construed to indicate that Zoloft is safe, effective or
appropriate.
