Parnate for Depression.
The following information is intended to supplement, not
substitute, the expertise and judgment of your physician,
pharmacist or other healthcare professional. It should not be
construed to indicate that using Parnate is safe or appropriate
for you.
People seeking depression relief should carefully evaluate Parnate
information and side effects before deciding to take Parnate.
Consult your healthcare professional before using Parnate.
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What is Parnate used for? Parnate is a monoamine oxidase
inhibitor (MAOI) antidepressant drug used
to treat the symptoms of depression.
General Parnate Precautions:
_ Tranylcypromine may cause drowsiness, dizziness, or blurred
vision. If you experience drowsiness, dizziness, or blurred
vision, avoid driving, operating machinery, or performing other
hazardous activities.
_ Rise slowly when rising from a sitting or lying position to
prevent dizziness or possible falls.
_ It is not known whether tranylcypromine will harm an unborn baby
or a nursing baby.
_ You are more likely to experience side effects from
tranylcypromine if you are over the age of 60.
_ Tell your doctor and dentist that you are taking tranylcypromine
before you have any type of surgery.
_ Parnate may impair judgment, thinking, or motor skills. Patients
using Parnate should exercise caution until they have adapted to
therapy.
_ If you skip the missed dose and take only the next one as
directed. Do not take a double dose of this medication. Overdose
is possible.
Parnate can cause serious side effects. Only you can decide if
Parnate is the best means of treating depression symptoms. It is
important to discuss the side effects of Parnate with your
physician.
Parnate Side Effects:
_ Headache.
_ Dizziness or drowsiness.
_ Insomnia.
_ Anxiety.
_ Agitation.
_ Tremors (shaking) or muscle twitches.
_ Weakness.
_ Abdominal pain.
_ Diarrhea or constipation.
_ Restlessness.
_ Nausea.
_ Decreased appetite.
_ Dry mouth.
_ Blurred vision.
Contact your doctor immediately if you experience: Severe
headache, large pupils, neck stiffness, nausea, vomiting,
sweating, irregular heartbeats, and chest pain. Contact your
doctor immediately if you have an allergic reaction (difficulty
breathing; closing of your throat; swelling of your lips, tongue,
or face; or hives). Contact your doctor immediately if you
experience yellowing of the skin or eyes.
Before taking Parnate, tell your doctor if you have or have
had:
_ Seizures or epilepsy.
_ High blood pressure.
_ Heart disease.
_ Kidney disease.
_ Liver disease.
_ Diabetes.
_ Pheochromocytoma.
_ Thyroid problems.
What should I avoid while taking Parnate? Avoid alcohol,
chocolate, cheese and all of the foods high in tyramine. Foods
high in tyramine can cause a severe reaction, including a severe
headache, large pupils, neck stiffness, nausea, vomiting,
sweating, irregular heartbeats, chest pain and death. Call your
doctor immediately if you experience any of these symptoms. Foods
that have high levels of tyramine include: Chocolate, caffeine,
cheese, yogurt, sour cream, beer (alcoholic and nonalcoholic),
robust red wines and especially Chianti, vermouth, homemade
breads, bananas, red plums, figs, raisins, avocados, fava beans,
eggplant, pickled herring, fish, beef or chicken liver, canned
meats, salami, bologna, pepperoni, summer sausage, game meat, soup
cubes, commercial gravies, soy sauce, yeast extracts and ginseng.
Symptoms of Parnate overdose may include: Symptoms of a
tranylcypromine overdose include hyperactivity, anxiety,
excitement, irritability, dizziness, insomnia, restlessness,
fainting, weakness, fatigue, flushing, sweating, hallucinations,
fast heartbeats, a severe headache, convulsions, coma, and death.
What other drugs will affect tranylcypromine?
Tranylcypromine can increase the effects of many other drugs,
leading to serious side effects. If taking Parnate, talk to your
doctor and pharmacist before taking any prescription or
over-the-counter medicines. Do not take Parnate with the following
medicines without your doctor’s approval:
_ Methylphenidate (Ritalin, Concerta).
_ Other antidepressant medicines. Serious and even fatal reactions
may occur.
_ Decongestants and diet aids that contain phenylpropanolamine,
pseudoephedrine, ephedrine, phenylephrine, and others.
_ Sleep medications.
_ Antiseizure medicines.
_ Heart medications.
_ Anesthetics.
_ Diabetes medications, including insulin.
_ Demerol.
_ Sulfonamides.
_ Diuretics.
_ Dextromethorphan - a cough suppressant found in many
prescription and over-the-counter cough and cold products.
_ Levodopa (Sinemet, Larodopa, Dopar).
*This antidepressant drug
information does not endorse Parnate, diagnose patients or
recommend therapy. The information contained herein is not
intended to cover all possible warnings, uses, precautions, drug
interactions, allergic reactions, or adverse side effects of
Parnate. If you have questions about the drugs you are taking,
check with your health care provider or pharmacist. The
information provided should not be construed to indicate that
Parnate is safe, effective or appropriate.
Do not stop taking Parnate without first talking to your doctor.
Your doctor may need to gradually reduce the dose before stopping
Parnate completely. Suddenly stopping Parnate may cause unpleasant
and potentially serious side effects.
